Blood circulation disorders often lead to lower extremity amputations (e.g., toe, foot, or leg), especially for older people. Circulatory disorders are mainly caused by calcification of the arteries, which doctors call arteriosclerosis. This condition causes blood vessels to narrow, known as stenosis, which can cause pain while walking. In more advanced stages of the disease, symptoms may also occur at rest. This can be caused by a lack of exercise, excessive body fat, smoking, high blood pressure, fat metabolism disorders or diabetes.
Diabetic foot syndrome
This syndrome is common in patients with type 2 diabetes mellitus. It is often accompanied by peripheral arterial vascular disease (PAOD), which is caused by diabetes. Both diseases make it more difficult for foot wounds to heal. People with diabetic foot syndrome often don’t notice until it’s too late, because their ability to feel, including pain, is significantly impaired.